Clinical Evaluation of Nervous System Abnormalities
This article provides a systematic approach to identifying, localizing, and diagnosing clinical manifestations of nervous system dysfunction in small and large animals. It emphasizes the importance of a structured neuroanatomical examination to establish accurate differential diagnoses.
Clinical summary
- Clinical signs
- Common clinical signs include ataxia, paresis/paralysis, altered mental status, cranial nerve deficits (e.g., anisocoria, nystagmus, facial asymmetry), tremors, seizures, and proprioceptive deficits.
- Possible causes
- Etiologies are broadly categorized using the VETSAID mnemonic: Vascular, Infectious/Inflammatory, Traumatic/Toxic, Structural/Congenital, Autoimmune, Idiopathic, and Degenerative/Metabolic/Neoplastic.
- Diagnostic approach
- Diagnosis is based on a structured neurological examination: mental status, cranial nerves, postural reactions, spinal reflexes, and muscle tone/atrophy analysis. Advanced imaging (MRI, CT) and cerebrospinal fluid (CSF) analysis are gold-standard diagnostic adjuncts.
- Management
- Treatment is etiology-dependent, ranging from anti-inflammatory and immunosuppressive therapy (e.g., corticosteroids) to anticonvulsants, surgical decompression for structural lesions, and supportive care for traumatic injuries.
References
- [1]Dewey, C.W.. A Practical Guide to Canine and Feline Neurology (2015)
- [2]Platt, S.R.. Small Animal Neurological Emergencies (2012)
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